The Treatment of Malaria with Peracrina 303

Sir,?In common justice to myself and to the manufacturers of Peracrina 303, I feel it my duty to comment shortly on the article by Dr. William Fletcher, published under the above title in the Indian Mcdical Gazette for November 1925. To begin with, Dr. Fletcher's disparagingly worded conclusion as to the composition of Peracrina 303, though apparently contradictory to the description given ?f the drug by the makers, does not in reality essentially differ from it. It is well known to every analytical chemist and every qualified medical man that " yeast cells" consist almost entirely of albuminates rich in medicinal value, and that unless the cells were " dead," they could not be used in an inorganic chemical compound ; further, that " a little starch " (or wheat flour) is invariably employed in the making up of pills, because of its binding properties. Acriflavine may be truthfully described as a ' yellow dye," though " an acridine dye